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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbd481c09001f107efe8490c1af0782b38c3336f7a033390ec090b4bd8af8380' 
  AND token = 'erqvgtAK0Hv7Z6CEZd7ub+AzLkBPwjnhHLfHrxDpvJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}