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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01fa724a3706c45d601b4b53b49434a13d18861e6c7ed2082ff11ec565b8967c' 
  AND token = '+84853m9ahC6kWPfi0u7XBnFejdYA1XNKMAV+AY4MtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}