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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '871b398bf4fc1d6ec3b89017fa7ba3c924913c378d7aa1906e5e615ece0ab320' 
  AND token = 'z+VF8mJtdpwpdBJuVcRR4oCVj1wNr7Bdnkr3PTb9amw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}