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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2341961e13e2d8bc261cf51036e80524c987082e948fbec44a9d876a7aac79b' 
  AND token = 'e7OJuDatI2+znfdt+VaRekaVxVSKlUzH5I3Htx75/iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}