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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757e3299faf2a0adcdd9d1ead4332ab574e5ead64631ac11063e6e3af618642d' 
  AND token = 'NtXJpGjoNaTgCyA2kKPvc9ShCY2bKyOD0D+8Tx7hKvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}