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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed26424a9cac0a8220e2834929a809b3afcc97931a1fc010b936a78e7f95e57' 
  AND token = 'T6dwH24o4IyV0K63rVoJ1MApSQrOajcJoKmwb240GBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}