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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0259aa6fc573c686fff9bba619e6f9c9e9349430f05c3bef74f71a030e7e27' 
  AND token = 'HftXjrokeLKNE/uOm9Dlm9NIu8GdXldHqZBdDWaJzCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}