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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b8b8117e9640fd21ad3b225f19f680a98c19c759d66900600e3a3278f48cf1' 
  AND token = 'TbSYUmGmZYdxdAXxuYEHk/YXiTH4U38/E180SCHwFR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}