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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce20c00e016587e06b9e69ffb1a8b8ebaacbc598b39342a51a934a2ccec97632' 
  AND token = 'dKKeS38T3anj/bMKd745i7+YF9CH9bnjPfufvL0a37I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}