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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9351b68a9a31bb472e4285c605664e19eb019b55fb1299a176e80b692c15614b' 
  AND token = 'QjCIhU5ZorbPMrP0H3aDtoaxtQIiE0gtwRAGTix8Yp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}