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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01fe7c0c3ec48738193972765920fae984b2db224fa544dc5e6a7f182b2cb6a1' 
  AND token = '3iCqn/4BXHHGhQz3aTOLVTptHOHkCyhsPYl11IoS3ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}