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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2066f68a4f0f84f21740bdfd8c13367c8264beb180e7d3b3ba14c7764a18048b' 
  AND token = 'sMfD6UU20u3DN5GoSdQJhaKUfzjsxOfv/gKAqoK62go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}