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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4ae6524a4ac99e5f43b55cb920f9e9e75d4f0fccd9a6d2dbcc25759f80875f' 
  AND token = '++XyOEQjssaXWhO8X8W8PbuzxQXcX2VTKPbK9Y6IQvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}