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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9784cd1d9a3ebe284a2ede10ccd0e57897d15f1acb1ef0b269643a0e47518363' 
  AND token = 'NXGpquR9jf1vQb1L2cTnKHX1519U/JNWRPmaSyRGVss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}