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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d1bf80b2bf55629a4e27f06ad98371358db0eee6ddc544214e52bd5bd97dfc' 
  AND token = 'ZlqPzZN7JPd+SuObhBM/dIy8G03S9vRIebsRRR6yF+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}