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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2544397744998a26e471019b2304465d67219f8e3d3ccc869ab8d98055cd2f81' 
  AND token = 'XSm+1k3bM6NMfM7FTnztzH2ei0yUCGj90GTmAoggfpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}