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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4478c570b3f3ed37d6d0bbda085a05c86f4bdb688d9b7c778dcdec2fc40acf' 
  AND token = 'WQmr1e2ZUWHgpLG1oYGePj9BnJEh8KbxuNvM845uKmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}