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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561a26a5f447f962daa5fa648b6534dc01868fa9537483df7a66daee6cc4ecf6' 
  AND token = 'tNxIZf7Q+Qru1GoWAunCWnAVJULNoFhfuMxtYnkYFac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}