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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd78d4686504f2f121299cd95366b9032a1c0c77e8a8662d373e374f44e9d287' 
  AND token = 'qe1hDUdq7qM5LAe2V5y1efvZeutuMqlLWLaIIphbjWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}