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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e447ed5aab15b9c470e38f3721b75d7bcef623a50bcb03ec654c662e5ee2d6d' 
  AND token = 'zMTNnBAR/nnI2Zi8W3VTE2wcMKmL6tZqtyW5BTORqWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}