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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cbe33db3ef1210d01de34da1a014c2014fe1966ab3de4d09b9635f97f44876' 
  AND token = 'egJ1SEhYaTySkF/NLRieTjXPGW49uEXARug7cs0zIjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}