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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c3713342903f81f9d5e4353460f8566a2ab79147f7c8f54686b1eaea717bd7' 
  AND token = 'yi6G0Mrxx68ZW9kdqzf5qoLMSb/hk0cVICN6dqMGu/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}