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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1eb4ca340ad2199ab5f08a769bdea37e2122589789d2b45f6924f4133a84e1f' 
  AND token = '+QXtthn3nfa5/ZY0R5xCFYn80BkIMBOuychd4xjv454=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}