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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84b9eb301edcc2bea78811a5d9830c0a5cde90a8109bb532abb75e8c7b835486' 
  AND token = '41LD9viIqcrg56PSC4L1A1jq7me4JfuCN6BVy4WXw2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}