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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e70963231be9a510883f6c21dce250d9b9d46aacce3e271bee868be40fffb8' 
  AND token = 'SadXTt9JagGvWK8TfPzGywVy3GTHOQxlfiA1wo+4sxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}