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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34c9814f7bd78dd1af721a042044c08f0e958821d3680ac5b4754f0387a4f6f6' 
  AND token = '/nv84+IlytZ7VT7EPmf/2YcbhIQFXxb5cixtBr5KirI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}