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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3803950e05203921ceced08d34b5810a8727ab8c6e687725e5bf7aad4bcbd2e0' 
  AND token = '+x/vM2it6d5OULCdxu8j5obsCIh1ZBVz8VuownEM4Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}