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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4915184a7bbeb722bb2e2eb102b59e497cdc184e9380c4ffb19ed6cdfa3e3c3' 
  AND token = 'IYCPwKXGPFSxPfEdTnDuEoU0tAzHc3cyzH2ndGISZ9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}