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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1187f2460ba68b87161439ca642c1a96cbbaf150280f9379b2abf864dd37a52' 
  AND token = 'o1IpuCCgdCUUrQ15jwX8mUIw5UC+JCW7vLgH38XAwZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}