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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a55b346ba88800a02e959c6c019d8fe14dfe9782cbd62744b22242ada0a3d6' 
  AND token = '44FEQdlzJQr6Gr44NXvXEDREsXlGPTYL+GNehhHr428=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}