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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ec1b0aaf9984793af33b648fb6e5b651043f4bd268b1db5b3de1625347a62f' 
  AND token = 'T6INHFcpGTOjTDlZIJLYUXiEHkWC9+QT8QS0vfN+i4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}