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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758d55b2439aacf4a355b8763991eb9c8409d6164e39369415e27e398d9a697b' 
  AND token = '+uWJo3/8fyy/1UBs6NiIZQbShbPgUGWZt27b+hNnkow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}