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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9855b10d90b26b6c39e83fd6b295d59da6316c339ac6507753ee0b26c1627021' 
  AND token = 'goVMD/rHYiUr7rQUJ6ILgpDJ382t2gYLPlGVs3IXmEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}