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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5853a216ec15e5c3a271601912f2c6b50034f1ab5dcdff8cdb418cfbd4595cae' 
  AND token = 'dOJWh/SN8IZiDIzhh0akU+etYlOPM2xUurw9fnyjVeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}