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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfbb411f6963a4ff74039ef4a7c062fa457f8fb55217b0b3b54437e465de2b7d' 
  AND token = '+hyhmdeXGkmEX+ebMtaiqIbaq6gtABLYJuIFsKpqgCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}