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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49637ff9e6bc74b9b81e20d2a0b310c0818a32b150fb4e1105ac8cb0c2e1dd63' 
  AND token = 'n2WznFR8BnS/pDo6uN85RsWsqzmK6NI8qjcKQAbid0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}