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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4779cbde9a7909fd83cc1106f7ee08b11b402110879448967c0f1f7bf08723bb' 
  AND token = 'wotd9EMh3Mlync0LooZGjvyqg1XHpSQxEUtuuaVPoOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}