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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57930bd429e1f8db2725f6eca4cb2aca6a468aa3c040e4fcd51563d7413faa48' 
  AND token = 'emHWSLNq+oy/eKB+SflcOinfg5xPH654KOeESn78pYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}