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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2377e345f7e5a13e61b37b649a65123d47c060edd104e060bdbd3ec90321726' 
  AND token = 'AAu3tFcSqDGTqy72hYzPEF3BzqVnklXGCECYGKfZ1nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}