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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c8aa983c83374b280a379e68d878d928e7c94b6981c2f276eed389bfad7d0a' 
  AND token = 'TmdBBZr282GcfyLQIIUqTGk1KIj4BM7KxYub0ZzNcrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}