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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f975c4bd247ad75c5b3067cc4b17f9a262bfa78c01b5be9ed143dff153afb21' 
  AND token = 'Gqyl7RvVaq4cxcSQxlAWtL02p7ReZSz6bAAYZh4r/4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}