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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f49ca60c45f33b3d88da53055bc8a153f378c646307e18e6a3dfba9f5bcdd0' 
  AND token = '1p2Y83UfHfJhRD61ljcG57NTneKIQduzlynS5K9c+oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}