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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dad44f1ad372f0334bc23bd434ca2c2657c7c19e368946e8dcefb414fde2d09b' 
  AND token = 'oIOIjSLSHJ5ooaO8uZAnEHEGCt+SdyR4qLfLsWx375c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}