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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357e4bef97c19b860076c03745056daa9d972347ad02d14420b2e4e9e06af244' 
  AND token = 'Tq/c28/eYwYdS22VDJ9ecH+wXVpkaBWTyUQF0OtqFmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}