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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b78a13bf657fac78de60c7131bbe13dafaf1982b8b36ea13da2bb0b3105b527' 
  AND token = 'WZ9MyySk5cH1RbbiWsBA9UUGBtyUQGHAjw/pcrvqL44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}