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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1588ef9960a99180b2d34a6fc0c5198f5311f2f06a1e3a2375cbd30b73b129a' 
  AND token = 'xOqc4npJE7/Rlj6UdVH+U/f5tyoFdR8NiQeBAejMouA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}