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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '532c33a522a95cf38a26f0a9ab7341c780488bd82f53076db49c47ff591f3241' 
  AND token = 'GNroq8/ttBPG5+V5ElAmNB/7OnS0u5ykmZEP8Ci1Pwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}