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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d330f3d54667b6ad2961512a315d030cc2a74289e122e762b0489365c359f9' 
  AND token = 'bCLmtOz3OS75WB8KMn4+S0w8BkgHoa/Kx072x1o7iNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}