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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387dd66082bd2e5978363d02ae7ffb283e900f1ecd184ff43b56497c9a210200' 
  AND token = '821tT/6qJhmdC2AtXMY1cAPZLuhRX4ke5gx/rUPa8hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}