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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943798cfcae340e7310a7417561d4150112e911dce1600408cde0ac3a3099c3f' 
  AND token = 'xSc6YEhZldNeuZ2dJfjak2Y2DopR/e3xCCOCmDkbW0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}